NoPhedra
NoPHEDRA, Absolute Nutrition’s revolutionary new formula is designed to burn fat without any
of ephedra's unwanted side effects. No jitters, nervousness, high blood pressure or insomnia.
NoPHEDRA is an extremely effective fat burning product without ephedra that really works!
It combines powerful, but safe, energy and mood enhancers, appetite suppressants and a synergistic
blend of potent fat loss agents.
NoPHEDRA provides a very powerful thermogenic and metabolic boosting effect for amazing long term results!
If you have been searching for the answer to ephedra, a way to actually burn fat and get lean without
ephedra, you’ve found it.
Technical Specs
- Green Tea & Caffeine
The green tea extract may play a role in the control of
body composition via the activation of thermogenesis and
fat oxidation.(*1)
Green Tea contains catechin-polyphenols
and caffeine. The catechin-polyphenols inhibit the enzyme
that tums off catecholamine activity.(*2)
Catecholamines are
responsible for the promotion of fat burning. The caffeine
works to promote catecholamine production and also
inhibit the enzyme phosphodiesterase. So this means caffeine
has the enhanced ability to burn fatty acids due to
the catechinpolyphenols and can act as an inhibitor of the
phosphodiesterase enzyme, which turns off fat burning.(*3).
- Synephrine
Citrus Aurantium (Advantra-Z™ ) is a Chinese fruit that
contains several alkaloids with Synephrine being the principal
compound. Synephrine is a related cousin of
Ephedrine and according to its patent information, it does
not act in the body as a stimulant. Synephrine is thought
to only stimulate the beta 3 receptors, which control basal
metabolic rate. This compound may provide the same fat
burning, muscle sparing and appetite regulation as
Ephedrine but with out any stimulant like side effects.(*4)
- L-Tyrosine
The amino acid L-tyrosine is converted to noradrenaline’
which is one of the catecholamines released by caffeine.(*5,6)
The L-tyrosine conversion to noradrenaline causes catecholamine
rejuvenation and prolongs caffeine effectiveness.
L-tyrosine is an amino acid that has been shown to
enhance the effects of other thermogenic agents.
- Forskolin
The newest ingredient to enter the fat loss arena is
Forslean® or the Ayurvedic
herbal Forskolin standardized
at 20% Coleus forskohlii. Research shows oral forskolin
to a potent stimulator of adenyl cyclase (*8)
Adenyl Cyclase
is the controlling agent of fatty acid beta-oxidation or to
put it simply when this enzyme is produced it forces the
body to burn fat for energy or fuel. If this herb is combined
with any beta-agonist say like synephrine it causes a
supercharged release of fatty acids to be utilized for energy
or fuel.
- Flavanex-ER
Flavanex-ER contains quercetin, naringin, and fisetin
which are bioflavonoids found to extend the actions of caffeine
and synephrine like compounds. This prolonged
action causes the caffeine and synephrine to work longer
and thus promote greater thermogenesis and fat loss.(*9)
- 5-HTP
5-HTP or 5-hydroxytryptophan has been shown to regulate
carbohydrate and food intake and thus promote fat
loss. 5-HTP is a precursor to serotonin. 5-HTP converts
5-HT or 5-hydroxy tryptamine (Serotonin). Serotonin is
thought to be one of the major hormones which regulates
carbohydrate and food intake.(10,11)
The HTP used is this product is of natural origin and is derived from the seeds
of Griffonia simplicifolia.
- REFERENCES
1. Dulloo AG, et al.Efficacy of a green tea extract rich in catechin polyphenols
and caffeine in increasing 24-h energy expenditure and fat oxidation
in humans. Am J Clin Nutr. 1999 Dec;70(6):1040-5.
2. Dulloo AG, et al.Green tea and merogenesis: interactions between catechinpolyphenols, caffeine and sympathetic activity. Int J Obes Relat
Metab Disord. 2000 Feb;24(2):252-8.
3. Leblanc, J. Etal.1985. “Enhanced metabolic response to caffeine in
exercise-trained human subjects” J Appl Physiol. Sep;59(3):p. 832-837.
4. Germano, C. 1998. “Advantra: The natural way to lose weight safely”
Kensington Publishing. Ch.2;p. 39.
5.Hull, KM, Et al. Effects of L-tyrosine on mixed-acting sympathomimetic-induced
pressor actions. Pharmacol Biochem Behav.1992
Dec;43(4):1047-52
6. Lehnert, H. Et al 1993. Amino acid control of neurotransmitter synthesis
and release: physiological and clinical implications” Psychother
Psychosom.60(1):p. 18-32.
7.ace, PJ., Matheny, M. et al.1996. Thermogenesis in brown adipose tissue
with age: post receptor activation by forskolin” Pflugers Arch.
Jan;431(3):388-394.
8.Fuhr U, et al Inhibitory effect of grapefruit juice and its bitter principal,
naringenin, on CYP1A2 dependent metabolism of caffeine in man. Br J
Clin Pharmacol. 1993 Apr;35(4):431 -6.
10. Ceci F, et al.The effects of oral 5-hydroxytryptophan administration on
feeding behavior in obese adult female subjects. J Neural Transm.
1989;76(2):109-17
11. Fickbohm DJ, et al. Localization and quantification of S-hydroxytryptophan
and serotonin in the central nervous systems of Tritonia and
Aplysia. J Comp Neurol. 2001 Aug 13;437(1):91-105
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