Andro Sports Creme (formerly AndrosteDERM)
Testosterone is the most important hormone in the male body. Yet
many men, of
all ages, suffer from decreased energy, diminished libido and reduced muscular size and
strength due to less than optimal levels of testosterone. Stress, over
training, obesity and aging are the most common causes for these problems. To put it
simply, without normal levels of testosterone, it is impossible to look and feel your
best.
When signaled by the pituatary gland in the brain the testes (gonads) produce
testosterone. But in order for the testes to be able to produce healthy amounts of
testosterone a number of nutritional substances are required including DHEA,
androstenedione, zinc, vitamin C, vitamin A and vitamin B6.
Maintaining high levels of these nutrients in the body are essential to assure that you
maintain healthy high levels of testosterone. Up until now, the only reliable way to
restore normal testosterone levels were through prescription testosterone replacement. But
recent clinical findings demonstrate that the use of these nutritional substances along
with the proper diet and exercise program will allow most people to once again produce
healthy, high levels of testosterone.
Introducing... Andro Sports Creme!
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Hormones
Andro Sports Creme (patent pending) is an all-natural, non-prescription nutritional product
that provides for the continually support of healthy levels of testosterone. Andro Sports Creme
uses a novel approach to delivering optimal ratios of the natural testosterone
precursors, androstendione and androstenediol, in a European
pharmaceutically-based topically applied gel.
Formulated by Dr. Rick Cohen, M.D., of MedLean, Andro Sports Creme contains a specially designed percutaneous gel matrix
to deliver natural testosterone precursors (androgens). Used for decades in
Europe, percutaneous gels have proven effective for delivering hormones to the
body. MedLean has taken this one step further by improving this technology and
adding in specific ratios of specially prepared testosterone precursors such as
androstenediol and androstenedione.
Andro Sports Creme has now clinically demonstrated that when used regularly, it is an
essential component for the successful restoration of healthy, high levels of
testosterone.
Initially formulated by a compounding pharmacy for use by Dr. Cohen's private
patients, Andro Sports Creme was made in the same manner as other pharmaceutical products. It
is currently still made to specifications by the exacting pharmaceutical standards and
by the same technology as that of the compounding pharmacy.
How does Andro Sports Creme work?
Andro Sports Creme is rubbed on the skin as a percutaneous gel
preparation. Over a period of several days, the testosterone precursors enter the body and
are slowly released into circulation via the lymphatic system. Tests have shown it
takes about three days to reach peak steady state levels. This is a true time release
technology.
What is the advantage of hormones in percutaneous gels?
- Percutaneous gel application of hormones only need be applied to the skin once daily.
Studies show that elevations in plasma levels remain constant throughout the day. The
adequacy of the dose can be checked by one blood or saliva sample. Where the matrix of the
transdermal patch acts as a reservoir for hormone delivery, percutaneous gels use the
natural reservoir of the skin to deliver a continuous flow of hormones into the body
between applications.
- Variances in individual plasma levels due to differences in skin absorption can easily
be corrected by adjusting the volume or strength of the gel used for the optimal
physiological effect.
- Combinations of 2 or more hormones can be combined into a single dose.
- There is no problem with skin irritations as is sometimes seen with transdermal patches
especially in warm and humid climates.
- The gels dry completely in 1 to 2 minutes leaving no visible trace or smell!
What are the benefits to using Andro Sports Creme over other andro products?
When used properly Andro Sports Creme has clinical demonstrated to
be safer, more effective and easier to use than oral andro products.
Once-a-Day Application - Topical delivery avoids having to time the use of the
product around meals and workouts. Apply it once a day in the morning and forget about it
while it works in your body.
Positive Results in Clinical Practice has clinically demonstrated that it
can provide the continuous natural healthy support of high levels of testosterone. And it
is this steady state high level of testosterone which is believed necessary to experience
the many benefits of testosterone including increased muscle size, strength, energy and
libido.
Why is Andro Sports Creme safer and more effective than other andro products?
- Improved Utilization - Andro Sports Creme bypasses digestion because it is applied
to the skin and not swallowed. The gel carrier avoids the waste that occurs with oral
products. It allows for more efficient use of the testosterone precursors in the body
providing a greater effect at a lower, safer dose.
More about how the first pass effect of the liver reduces utilization:
While it is reasonable to assume that the oral route is less optimal because stomach acid
probably destroys the hormone during digestion, this is not true. Steroid hormones such as
DHEA, androstenedione, and androstenediol, are quite stable during digestion and are
absorbed fairly well. The reason swallowing these hormones is not the optimal way to take
them is before they enter the blood stream where they can be converted into testosterone
they are metabolized in the liver, the so-called first pass effect of liver
metabolism.
The liver is responsible for converting many hormones into inactive metabolites that can
then be excreted from the body. By bypassing digestion with Andro Sports Creme, the enzymes
responsible for converting these pro hormones (17ßHSD and 3ßHSD) into testosterone can
do their job before they reach the liver and are converted into non active metabolites
and/or excreted from the body. This means that a higher percentage of these androgen
precursors can be converted into the parent hormone (testosterone) using a much lower dose
than is needed when taken by mouth. These factors make Andro Sports Creme a superior choice to other
andro products both in terms of cost and effectiveness...guaranteed.
- Continuous Support of Healthy Testosterone - Topical delivery provides
steady state support of testosterone production. It does not cause the spikes
seen with high doses of oral Andro products, just higher levels with normal daily
fluctuation. And it is these high steady state levels of testosterone that are necessary
for optimal support of healthy normal muscle and biochemical function.
More about topical gel pharmacology:
Andro Sports Creme causes a steady state level of testosterone. Other andro products must be taken
by oral administration (swallowed) and only cause a temporary spike in testosterone
levels. If you want to keep a steady state level of the hormone in the body, you must take
these andro products by mouth every 2-3 hours. This is expensive and wasteful.
With a single dose applied to the skin once per day, it takes about three days for
Andro Sports Creme to reach "steady state" levels of increased production of testosterone.
It is these steady levels that are believed to be more anabolic than the temporary spike
achieved with the oral intake of any anabolic hormone, especially testosterone and its
precursors.
Another advantage to steady state levels is because the limiting factor in
converting these precursors to testosterone is the ability of the body to replenish these
enzymes, high one-time dosages that cause spikes will probably overwhelm the capacity of
the body's enzymes and spillover is more likely to take place. This means
the body may convert the hormones into unwanted metabolites which reduce the effectiveness
and possibly increase the likelihood of side effects. Lower multiple dosages or steady
state release ensures better utilization and more complete conversion.
- Enhanced Conversion of Androgen Precursors to Testosterone
The optimal combination of androstenedione and androstenediol in a steady
state delivery allows for more efficient enzymatic conversion to testosterone.
Why?
It seems that the 3ßHSD enzyme that converts androstenediol to testosterone is not
subject to the same rate limiting factors that the 17ßHSD enzyme is that converts
androstenedione to testosterone.
The 17ßHSD enzyme requires high ATP levels, therefore it may require large amounts of
carbohydrates or supplements that support liver ATP such as pyruvate, phosphates and
niacin to function optimally and it is also less active in men than in woman.
So why use androstenedione at all?
Because there is a theoretical reason to combine both androstenedione and androstenediol.
Due to the fact that they use different enzymes for conversion to testosterone, when used
together they have an additive effect in enhancing testosterone production while at the
same time minimizing the potential for overloading either enzyme. This allows increased
benefits with a reduced potential of unwanted effects or waste.
Who can use Andro Sports Creme?
Anyone interested in maintaining high healthy levels of testosterone. These include:
- those who physically train hard either for strength or endurance. (Weightlifters,
triathletes, runners and bikers all can benefit)
- those who show the signs of aging including decreased lean mass, strength, energy and
libido.
- those who as part of a comprehensive diet and exercise program want to naturally restore
optimal levels of testosterone.
Who should not use Andro Sports Creme?
- Women who are sensitive to androgens.
- People with any pre existing hormonal dependent cancers (i.e. prostate, breast, etc.)
should avoid ALL andro products until more is known regarding the relationship of the
testosterone precursors and the above afflictions.