Xenadrine Energy 8-Hour

New Xenadrine Energy 8-Hour is a revolutionary new extended-release energy supplement which utilizes a unique "power-pellet" delivery system. Its patented formula is specifically designed to help increase energy levels within thirty minutes and then keep on working to maintain those levels for up to 8 full hours.

What does it do?

The secret to Xenadrine Energy's effectiveness resides in a remarkable combination of natural ingredients. First is Norambrolide™. This fermented sage compound has been shown in unpublished in-vitro research¹ to increase levels of a cellular messenger called cAMP (cyclic adenosine monophosphate). The significance of this is that in some metabolic processes, cAMP is involved in activating cellular enzymes and other substances that help move fat out of the fat cells and promote the weight loss process; although no research has yet been done to demonstrate that Norambrolide™ will have this effect in humans.

Next is the proprietary Thermozanthin™ blend. This includes Yerba Mate, Guarana, Green Tea and Cocoa seed extract; each of which are sources of methylxanthines. Journal articles have identified methylxanthines (e.g., caffeine) as having thermogenic activity (heat producing which leads to the body burning more calories) in human² and animal³ research. Furthermore, green tea extract has been demonstrated in a randomized, placebo-controlled study to increase weight loss and burn calories.⁴ Other research⁵ on green tea has shown similar results. The Thermozanthin™ blend also contains the amino acid l-tyrosine. Tyrosine is a precursor to catecholamines like norepinephrine and dopamine ⁶, which are integral to the body’s fat burning processes. Also included in the Thermozanthin™ blend is green coffee bean extract. In human research the chlorogenic acid in coffee has been shown to reduce the amount of carbohydrates absorbed. ⁷Furthermore, animal research using isolated chlorogenic acid demonstrated that this compound has the ability to reduce the amount of glucose that can be created from metabolism of carbohydrates and proteins.^8,9 The potential benefit is that when the body is unable to derive energy from these sources, it may draw upon stored sources of energy (such as body fat) to help meet energy needs; although no research has yet been done to demonstrate that green coffee extract will have this effect in humans. Rounding out this formula is vitamin B12, a nutrient necessary in the maturation of red blood cells (which carry oxygen for energy metabolism). It should be noted that many of the natural ingredients in this formula support energy metabolism.

Note: Individuals who typically consumer caffeine containing beverages on a daily basis are less likely to feel a difference using only the standard serving. CAUTION: Do not take more than 4 tablets in an eight hour period. A standard serving of this product contains about 300 mg of total methylxanthines (including caffeine), which is the amount typically found in a 10 oz. cup of coffee. Too much caffeine may cause nervousness, irritability, sleeplessness, or occassionally, rapid heartbeat in some individuals. This product also contains theobromine and theophyllin, methylxanthines related to caffeine. Individuals who are sensitive to caffeine may also experience sensitivity to these methylxanthines. Consult your physician prior to using theophylin if you are using asthma medications.

References:
¹Anonymous. Sclareolide Effect on cAMP in Two Cell Lines. Unpublished report by NovaScreen. 2003; 19 pp.
²Bracco D, et al. American journal of physiology 1995; 269(4 Pt 1):E671-8.
³Dulloo AG, et al. Metabolism-clinical and experimental 1992; 41(11):1233-41.
⁴Dulloo A, et al. Am J Clin Nutr 1999; 70:1040-5.
⁵Chantre P, et al. Phytomedicine 2002; 9:3-8.
⁶Green R. Human Hormones. New York: McGraw-Hill; 1970:55-61
⁷Johnston KL, et al. Am J Clin Nutr 2003; 78(4):728-733.
⁸Arion WJ, et al. Archives of Biochemistry and Biophysics 1997; 339(2):315-322.
⁹Hemmerle H, et al. Journal of Medicinal Chemistry 1997; 40(2):137-145.