6-OXO contains a naturally occurring aromatase inhibitor that is devoid of any direct hormonal or pro-hormonal activity (androgenic or estrogenic). It is what science refers to as a "suicide inhibitor" of aromatase. Specifically this means that it will irreversibly bind to the aromatase enzyme and permanently deactivate it. With prolonged use of 6-OXO, the result will be a very substantial reduction in the production of estrogen in the body, along with a coinciding up-regulation of natural (testicular) testosterone production. 6-OXO works at the level of the brain to stimulate the production of FSH and LH - not decrease it. The result is an increase in testosterone, an increase in spermatogenesis (fertility), and quite possibly even an increase in testicular mass.

6-OXO should be taken at night because that is when endogenous estrogen production is maximized.

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