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Molecular Nutrition logo
1-T Ethergels 1-T Ethergels

Molecular Nutrition's new 1-T Ethergels contain the steroidal nutrient 1-testosterone tetrahydropyranyl (THP ether), dissolved in sesame oil and sealed in a soft gelatin capsule for maximum lymphatic system absorption, oral bioavailability and anabolic effect. This type of delivery vehicle is absolutely essential for ether-modified hormones, as it allows for a level of absorption many times greater than simply putting the compound in a regular hard-shell capsule. 1-T Ethergels are the first in a revolutionary line of new oil-solubilized, softgel encapsulated prohormones from Molecular that promise to tackle, once and for all, the issue of poor prohormone bioavailability.


1-Testosterone THP ether
(5a-androst-1-ene-3-one,17-tetrahydropyranyl)

1-Testosterone
(5a-androst-1-ene-3-one,17b-ol)

...the first in a revolutionary line of new
prohormones from Molecular that promise to tackle,
once and for all, the issue of poor prohormone
bioavailability.

ETHER-MODIFIED 1-TESTOSTERONE

Ether-Modification is a breakthrough in the field of steroidal nutrients, as it allows us to drastically increase the oral bioavailability of hormonal supplements by altering the way they are absorbed by the body. The technology works by attaching an ether molecule to a steroidal hormone, which tremendously increases its lipophilic (fat-soluble) nature. This allows much of the active hormone to bypass the destructive first-pass through the liver, and instead enter circulation, intact, through the lymphatic system. With this technology there is simply no longer a need for high doses or alternate forms of delivery!

SUPERIOR SOFTGEL FORMULATION

But if we just put our 1-Testosterone ether in a regular capsule we would have wasted its true potential! Maximum lymphatic absorption is achieved only when the ether-modified hormone is dissolved in a proper oily vehicle. The graph below illustrates this significance extremely well with mepitiostane, an ether-modified form of the steroid epitiostanol. Here steroid absorption by the lymphatic system was more than 5 times greater when dissolved in sesame oil rather than a water-based solution. This is a monumental difference, and the reason our softgels use exactly sesame oil as their vehicle. With unquestionably the best possible oral absorption and anabolic potency of any steroidal nutrient on the market, our 1-T EtherGels™ are without doubt the ultimate 1-testosterone supplement, Hands Down!

…absorption by the lymphatic system was more
than 5 times greater when dissolved in sesame oil…

Figure 1. Differences in lymph absorption when ether-modified steroid is administered in sesame oil vs. a water-based vehicle to the small intestine of rats. SOURCE: Effect of oily vehicles on absorption of mepitiostane by the lymphatic system in rats. Ichihashi T, Kinoshita H, Takakishi Y, Yamada H. J Pharm Pharmacol 44 (1992) 560-4.

A NATURALLY OCCURRING HORMONE

1-Testosterone (5a-androst-1-ene-3-one,17b-ol) is an androgen metabolite found in humans. It is similarly a natural compound that can legally be sold as a nutritional supplement.

1-T Ethergels stack well with 4-AD Ethergels for best results.


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