Myo-T12 is a myostatin modulator clinically validated to reduce average serum myostatin levels in only 12 to 18 hours with just a single serving.*

Myostatin is a protein produced by a specific gene sequence in the DNA of nearly every vertebrate animal. Controlling myostatin is the holy grail of extreme muscle growth.

MYO-T12 was developed to help men gain muscle. It is not recommended for women.

See Myo-T12 Q&A Below.

Myo-T12 (Peak Wellness BioPharma) - Average rating (1 review)  - Write a review Show Reviews Reviews 1 of 1 people found the following review helpful. March 07, 2010 Reviewer: Shawn in Colorado I had a lot of faith in this product after reading about it in Muscular Developement Magazine. I was very excited to get it and see the results. In the end I was very disappointed. I just finished using the whole container. During its use I held my regular workout rotation and worked very hard to make gains. For the last few days of use I even tried taking it every 18 hours instead of every 24. I didn't make a single pound of muscle gain from using this product along with creatine/protein supplementation and an intense workout schedule. Was this review helpful to you? Yes  No

591-0001 Peak Wellness BioPharma Myo-T12 300g Nutrition Facts Serving Size: 1 Scoop (10g) Servings Per Container: 30 Amount Per Serving % Daily Value* Total Calories 50         Calories From Fat 0      Total Fat 2.5  g 4%       Saturated Fat 1  g 5%       Trans Fat 0  g   Cholesterol 35  mg 12%    Sodium 10  mg 0%    Total Carbohydrates 5  g 2%       Dietary Fiber 2  g 8%       Sugars 3  g   Show Net Carbs Net Carbs Minus Fiber 3  g Protein 2  g   Vitamin A     45%    Vitamin C     0%    Calcium     0%    Iron     4%    *Percent Daily Values are based on a 2,000 calorie diet. Ingredients: Fecunded G, gallus domesticus isolate (fertile egg yoke powder), fructose, natural and artificial flavor. Recommended Use: As a dietary supplement, take one serving at mid-day. Mix one scoop in approximately 6-8 oz of cold water and consume immediately. Warning: KEEP OUT OF REACH OF CHILDREN. ALLERGEN INFORMATION:This product contains egg products and/or it's components. Read and follow all label instructions prior to use. Not for use by females or anyone under the age of 18. Consult with a physician before using this or any other product, if you are taking medication or have any medical condition. Do not cook with this product or add to hot water. Before beginning any program of weight loss, consult your health care practitioner. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. If you notice any errors in the information above, please let us know. If you have further questions about this product, please contact Peak Wellness BioPharma at 732-920-4637

From The Manufacturers Website:

MYO-T12 Q&A

What is myostatin and why is it so important for muscle growth?

Myostatin is a protein produced by a specific gene sequence in the DNA of nearly every vertebrate animal. Controlling myostatin is the holy grail of extreme muscle growth.

Why would your body need myostatin?

It has been theorized that this vestigial control over muscle gains was needed to prevent an organism from being overly muscled and thus fall more easily to predation either because they would have been too bulky to speed away or because they just looked more delicious. So through Darwinian selection, having little or no myostatin has become exceedingly rare among animals and humans. Nevertheless those rare survivors live normal, happy, albeit well-muscled lives. As examples, the Belgian Blue bull and the Piedmontese breeds are born without the gene to produce myostatin. From a health standpoint, these animals are not at all adversely affected by the absence of myostatin.

Since we don't have much use for myostatin, is it dangerous to have none?

So far it seems that health is not affected by naturally having little or no myostatin. For example several years ago a little German boy was discovered to lack the gene for producing myostatin. It was reported in the New England Journal of Medicine and scientists have been following him for years. Thus far he is normal and healthy in every way, except for the fact that he is exceedingly well-muscled and super strong. Other athletes, like professional bodybuilder Flex Wheeler have been identified as having a dysfunctional gene for myostatin.

Are the pharmaceutical companies working on drugs to inhibit myostatin?

Yes. Drug companies are pushing hard to invent some kind of synthetic molecule they can patent. In particular the industry is hard at work developing vaccines to knock out natural production of myostatin. MYO-029 was a recombinant antibody that bound and neutralized the body's myostatin. In other words, it was an immunologic drug that caused an unnatural antibody attack on the body's own myostatin. Even at that extreme, preliminary published safety data seemed to support its relatively safe use. But research on the drug was mysteriously abandoned by Wyeth. Without being privy to the unpublished data, I can just say as a medical doctor that I don't like the idea of the vaccines because they likely would permanently eliminate all myostatin from the body in people that are otherwise used to having some. So this vaccine approach is not without concern and thus ultimate use of these types of drugs appear relatively far away and will likely be very restricted.

Are there natural myostatin inhibitors that don't operate like these experimental vaccines?

Yes. In fact it's in our food supply! When properly handled to preserve the yolk membrane and accompanying blastodisc, fertile chicken egg yolk can effectively and naturally down-regulate myostatin in humans in a serving-size dependent manner. In other words we can regulate the reduction by way of the amount of fertile egg yolk ingested.

Can't I just eat lots of fertile eggs to get the same result?

In theory, you could, but be prepared for some major challenges. Fertile eggs are tough to find and relatively speaking, very expensive. More importantly, standard commercial store-bought fertile eggs are heat pasteurized at a temperature that inactivates most of the active myostatin inhibitors. So it won't have much biological activity. But with some of this stimulation, to get in enough you would still be contending with gulping down huge amounts of calories, largely from cholesterol and fat from what would be dozens upon dozens of eggs you would end up having to eat. This has yet another consequence-gas. If you choose this route, be prepared to spend lots of quality time in the bathroom. Thus trying to eat all those fertile eggs is not practical, either economically, physiologically, or gastronomically. So with standard store-bought fertile eggs, even if you could afford them plus manage to stomach eating enough of them, you still would not likely get the effect you had hoped for in terms of substantially lowering your myostatin.

Is it safe to assume that unless I live on a farm with unlimited access to fresh fertile eggs and I love eating a lot of them, I won't likely see the benefits of their ability to inhibit myostatin?

Precisely, fertile eggs are not only eaten in mass quantity in other countries but historically have been eaten and continue to be eaten in large amounts on American farms across our great country. Who knew?-Maybe that's why we always see these massive country boys coming out of the mid-western and western states! But again, we're talking about years of eating lots of farm-fresh fertile eggs, which is impossible for most of us.

Has natural food technology helped us out here?

Certainly, we know how easy it is to naturally debulk and separate an egg. Just look at all the bottled egg whites sold in every major grocery store in America. These are consumed by athletes, bodybuilders, and the health conscious literally from coast to coast. That said, we can, in theory do the same thing with the yolks. Of course few people would by bottles of yolk because of the high amount of calories, saturated fat, and cholesterol. The point is, in theory, it's no different-six of one and a half dozen of another. Now if you take that same debulking separation technology and apply it to the fertile egg, you effectively amplify the naturally occurring factors that inhibit myostatin.

Is an average reduction of serum myostatin of 11.32% enough to make big gains in muscle?

That's tough to say. While certainly impressive data representing a major reduction in myostatin, we already knew thanks to our research colleagues at Johns Hopkins University in a 2001 published study proving that if there is as little as a 20% reduction in serum myostatin, the result will be a very significant increase in muscle mass. So we were hoping for at least a 20% decrease in this larger group and thus we knew we were on the right track.

Since that study back in 2008, has there been any progress in terms of creating a better fertile chicken egg yolk product properly handled to preserve the yolk membrane and accompanying blastodisc?

Absolutely, after establishing a carefully selected group of procedures and proprietary sequence of steps, including a new method not previously available to us, a new "high grade handling" method was set to be tested. In February of 2009 our sample was 3rd party tested and confirmed to have an exponentially higher active potential then the old Folstaxantm! So was born MYO-T12tm.

Has MYO-T12tm been specifically tested in humans?

Yes. In April of 2009 I tested Myo-T12tm to see its effect on myostatin and if it truly was better than Folstaxantm. Recall that the results of a prior study on Folstaxantm produced an average reduction of serum myostatin at 24 hours of 11.32% in seven subjects ingesting 20 grams of product, with two non-responders. In contrast, MYO-T12tm was tested in 10 healthy adult male human subjects at only a single 10 gram serving size. After baseline myostatin testing, subjects received a single MYO-T12tm serving of ten grams. Baseline results before ingestion showed an average level of 27.5pg/ml. At between 12-18 hours after dosing the average serum myostatin declined to 12.6pg/ml with every subject responding positively! This was a staggering 46% drop in myostatin from baseline across all ten subjects! Add to that, unlike the previous study done on the old Folstaxantm where 2 out of the seven subjects were non-responders, here all ten subjects responded. Finally, at the 24-30 hour time point with a mean value of 28.1pg/ml, the average myostatin level completely normalized.

How landmark was this study?

This latest study was critical in that, with it, I finally had the results that demonstrated once and for all that the new method of high-grade handling was more effective than anything seen to date. The dramatic 46% drop in myostatin at 12 hours that just bowled me over, and so was born the name MYO-T12tm (a name I chose to underscore the myostatin inhibiting effectiveness at the 12 hour point). Of course I should point out that I was equally pleased with the complete normalization of myostatin levels in test subjects after 24 hours. In this way it's nice to know that, should you decide to not take a subsequent serving of the product, you can expect your levels to return to what they were within a matter of hours.

We've seen dietary supplements in the past that were supposed to be myostatin inhibitors but didn't work. How is MYO-T12tm different?

Past myostatin inhibitors marketed as dietary supplements simply didn't end up working. The problem was that the only data to support their efficacy at inhibiting myostatin was that in a test tube or loosely based on somewhat unrelated animal studies. The main ingredient was a brown sea algae called cystoseira canariensis. The resident expert on the subject of cystoseira canariensis as a purported myostatin inhibitor is a D.S. Willoughby from the Department of Human Performance at Baylor University in Texas. Willoughby reported that cystoseira canariensis in two studies formulas containing cystoseira canariensis had no effect on muscle mass and strength. In addition, these products had no effect on serum myostatin levels! In sharp contrast, MYO-T12tm has been demonstrated with a clearly understood mechanism of action in the human model to reduce serum myostatin levels.

How does MYO-T12tm compare with testosterone or human growth hormone?

We as yet remain unsure of the true maximum muscle potential of MYO-T12tm. But it may very well emerge as the single most powerful approach to building massive muscles in otherwise healthy male subjects.

How soon should I see a difference from taking MYO-T12tm?

In the case of MYO-T12tm it's a chain of hormonal events culminating in a completely reversible decrease in serum myostatin within 12-18 hours after ingestion. After that, the direct effect on muscle has not been precisely detailed in the scientific literature. But we do know that it takes some time. It has been theorized that in much the same way as anabolic steroids, which take at least five weeks of regular ingestion to start to see the early gains, with real noticeable muscle gains not starting for at least eight to twelve weeks. After that, based on the John Hopkins University data that a 20% reduction in serum myostatin promotes very dramatic muscle growth, I theorize that, with consistent daily serving sizes, the gains should be quite regular and continuous.

How does the strategy of inhibiting myostatin compare with just taking my chances abusing anabolic steroids and growth hormone?

Abusing anabolic steroids and growth hormone is simply stupid. Abusing these drugs is fraught with dangers, while myostatin does not even work on the same axis as these substances. Furthermore, the strategy of temporary and periodic inhibition of myostatin actually blows away anything and everything that we know about the ergogenic gains we see from these performance enhancing drugs. There is no question in my mind that myostatin inhibition is the holy grail of extreme muscle building. The as yet unanswered question that lay ahead is how we best manage this strategy. To me, right now, the best and only natural way is MYO-T12tm.

How often and how much MYO-T12tm would you have to take the product to keep Myostatin levels at a minimum?

It is difficult to say with any certainty precisely how much MYO-T12tm one would have to take too keep myostatin levels at a minimum since this specific research has not been performed. But keep in mind that the idea is to take it as did the study subjects only once in a day, thereby allowing myostatin to return to baseline. If one ignores the directions and takes two or more MYO-T12 servings at one time or ingests it more frequently, one might theoretically achieve an even greater drop or perhaps sustained drop in serum myostatin. But, this goes against the idea of temporarily modulating myostatin and allowing the level to periodically and regularly return to normal limits. So the idea of MYO-T12tm is to simply give you a natural edge. Apart from the fact that excessive servings beyond the recommendations simply has not been tested, if you are gobbling it down in excess trying to look like a Belgian blue bull, such stupidity cannot be advised or recommended.

Is there any actual evidence to suggest that 3 months of supplementing with MYO-T12tm will increase muscle mass?

There is currently no conclusive proof that shows three months of supplementing with MYO-T12 will produce an increase of muscle mass in everyone who takes it this way simply because this research has yet to be performed. We can only extrapolate what we know from other published research about serum myostatin and how reducing its level effects muscle mass.

If the effects of MYO-T12tm are temporary, does that mean GAINS are temporary?

MYO-T12 is intended to temporarily reduce myostatin levels. It is not intended to be taken so often or in such amounts that one shuts down myostatin production altogether. This influence is intended to give you an anabolic edge when training hard while not permanently altering your hormonal landscape. Once you earn them with hard training, gains are gains. If you stop training or train unintelligently, no supplement or drug in the world is going to keep or improve your gains.

Does MYO-T12tm need to be cycled?

It is my belief as the principle researcher that nearly every drug and dietary supplement known to man should be cycled whenever possible. This avoids a condition called tachyphylaxis (a term used to describe how the body gets used to something rendering it ineffective). Generally speaking, some top experts recommend a break for at least a few weeks from drugs and/or supplements at least a couple of times each year.

Can MYO-T12tm be stacked with other products (pro-hormones, test boosters, creatine, etc...)?

As far as we know at this time, MYO-T12tm does not work of the same axis as do the pro-hormones, testosterone boosters, or creatine. These substances do not directly influence myostatin levels, so their presence would not likely either detract or enhance the effect of MYO-T12tm on serum myostatin. Nonetheless, if there is muscle building synergy with these stacked ingredients, we simply do not yet know.

Should women take MYO-T12tm?

MYO-T12tm is a product that I intended to help men gain muscle, and never intended for women to take it. Also MYO-T12tm has simply never been tested in women. So I would say no.

What type of flavoring or sweetener is used?

MYO-T12 is sweetened with fructose and contains no artificial sweeteners or sugar substitutes.

How does MYO-T12tm taste and mix?

MYO-T12tm has a light vanilla taste with a sweet flavor. There are no artificial sweeteners or natural sugar substitutes in the product. Though there are no large clumps, it does mix up with a slightly grainy texture. But there's a good reason for this. The active ingredients in MYO-T12tm tend to be heat sensitive resulting in deactivation. Excessive drying can involve heat. So to be on the safe side of preservation of biologic activity, the product is manufactured a touch on the side of not being fully dried (desiccated). So if the product seems a little clumpy, it is by intention, though we are in the process of working on methods to improve this facet.

So does that mean I shouldn't cook or bake with it?

Do not cook MYO-T12. You'll be throwing your money away. Not only should you not cook or bake with MYO-T12tm, but you should not even add it to hot liquids. It is best mixed directly in water or perhaps in a blender with cold contents.

Could MYO-T12tm help people with diseases like muscular dystrophy, AIDS, and other conditions where muscles waste?

MYO-T12tm is specifically sold as a dietary supplement and not meant to treat any disease. Though there have been a number of stunning reports of early generations of the product being remarkably beneficial to certain people with medical conditions, these are nothing more than case reports and have in no way been substantiated. As such, they should not be taken in any way as proof that MYO-T12tm has any ability to treat, cure, or reverse a given disease or affliction.

How do you take MYO-T12?

One canister of MYO-T12 currently contains 300grams of product, which should equate to approximately a one month supply (i.e., a daily serving of 10 grams for 30-days). The instructions specifically state “Mix one scoop in approximately 6-8 ounces of cold water and consume immediately”. A challenge we have had centers on getting the scoop size precise enough to accommodate both the natural state of the product with its slight variations in clumping and fluff in conjunction with the variable scooping techniques of different consumers. Obviously the best way to make sure you get the precise 10 gram serving is to weigh it out. But this is impractical. So while we continue to refine production to create a better flowing, less clumpy, and more consistent product, we have adjusted the scoop size to better approximate a proper serving size.

What kind of results should I expect with MYO-T12?

While our recommendation is to not expect significant results in less than three months of supplementing with MYO-T12, consumers must realize that there is currently no conclusive proof that shows three months of supplementing with MYO-T12 will produce massive results in everyone simply because this research has yet to be performed. We can only extrapolate what we know from other published research about serum myostatin and how reducing its level effects muscle mass. What we do know is that MYO-T12 has been shown to temporarily cut myostatin levels in humans by nearly half in as little as 12 hours, while returning levels to normal in as little as 24 hours. Again, the idea here being to allow the level to return to baseline and not forcing it to constant zero, as do many of the drugs in development. The idea is to take the product as did the study subjects only once in a day, thereby allowing myostatin to return to baseline. If one ignores directions and takes two or more MYO-T12 servings at one time or ingests it more frequently than recommended, one might achieve an even greater drop in myostatin. But, this goes against the idea of temporarily modulating myostatin and allowing the level to periodically and regularly return to normal limits. So the idea of MYO-T12 is to simply give you a natural edge. We do not want to make people into freaks. Apart from the fact that excessive servings beyond the recommendations simply has not been tested, if you are gobbling it down in excess trying to look like a Belgian blue bull, such stupidity cannot be advised or recommended. Finally while we are getting extraordinary reports of product gobblers taking excessive amounts of product and getting huge beyond belief, we will not publish those stories or photos as they are idiotic and not representative of the intended use of the product. Furthermore, MYO-T12 is intended to temporarily reduce myostatin levels. It is not intended to be taken so often or in such amounts that one shuts down myostatin production altogether. This influence is intended to give you an anabolic edge when training hard while not permanently altering your hormonal landscape. Once you earn them with hard training, gains are gains. If you stop training or train unintelligently, no supplement or drug in the world is going to keep or improve your gains.