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1 of 1 people found the following review helpfulApril 14, 2016Reviewer: Kathy in New York* I started using Topricin cream because I have some arthritis in my thumbs. I also have carpal tunnel syndrome which causes my fingers to go numb while I'm sleeping. About a week ago, I started rubbing Topricin cream on my hands AND wrists before I go to bed. I found that I get NO numbness in my fingers while I sleep. Definitely worth continuing use.